Table 3.
Adverse Reaction | Day 0 | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | |
---|---|---|---|---|---|---|---|---|
Local | Maximal diameter of redness or swelling at the injection site, cm | |||||||
≥ 1 cm and < 5 cm | 2 (12.5) | 1 (6.25) | 1 (6.25) | 4 (25) | 4 (25) | 2 (12.5) | 0 (0) | |
≥ 5 cm and < 10 cm | 3 (18.75) | 6 (37.5) | 3 (18.75) | 2 (12.5) | 1 (6.25) | 0 (0) | 0 (0) | |
≥10 cm | 0 (0) | 2 (12.5) | 3 (18.75) | 1 (6.25) | 1 (6.25) | 0 (0) | 0 (0) | |
Mild soreness in arm | 5 (31.25) | 3 (18.75) | 2 (12.5) | 6 (37.5) | 4 (25) | 2 (12.5) | 1 (6.25) | |
Moderate soreness in arm | 2 (12.5) | 5 (31.25) | 4 (25) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Severe soreness in arm | 0 (0) | 1 (6.25) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Systemic | Nausea | 0 (0) | 0 (0) | 1 (6.25) | 1 (6.25) | 1 (6.25) | 1 (6.25) | 1 (6.25) |
Headache | 1 (6.25) | 2 (12.5) | 3 (18.75) | 2 (12.5) | 2 (12.5) | 2 (12.5) | 2 (12.5) | |
Myalgia | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Arthralgia | 0 (0) | 1 (6.25) | 1 (6.25) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
Fatigue | 2 (12.5) | 5 (31.25) | 4 (25) | 2 (12.5) | 1 (6.25) | 1 (6.25) | 3 (18.75) | |
Temperature ≥38°C | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
All data are presented as n (%) of participants (N = 16).