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. 2020 Mar 4;16(9):2222–2237. doi: 10.1080/21645515.2020.1713605

Table 4.

HIA serum titers and percent virus neutralization in DRAGA mice sublethally (LD50)-infected with A/H3N2 Hong Kong or A/H3N2 Victoria virions. (as per Figure 10).

HK-infected mice # dpi M1 M2 M3 M4 M5 F1 F2 F3 Humans era
HIA titers   1:40 1:40 1:40 1:100* 1:100* 1:20 1:20 1:40     1:320**
Percent of virus neutralization   40 40 40 100 100 20 20 40      
Victoria-infected mice # 32 M1 M2 M3 M4 M5 F1 F2 F3 F4 F5  
HIA titers   1:20 1:20 1:20 1:20 1:80 1:20 1:40 1:40 1:40 1:120* 1:560**
Percent of virus neutralization 32 16 16 16 16 66 16 33 33 33 100  

M1-M5 male mice and F1-F3 female mice infected with Hong Kong virus and assessed at 32 dpi; M1-M5 male mice and F1-F5 female mice infected with Victoria virus and assessed at 32 dpi. * Highest HIA titer to the virus. Percent viral neutralization among individual mice was calculated based on the highest HIA titer in each group. ** HIA titers of a vaccinated individual with 2014 AFLUVIA vaccine and assessed in 2015.