Table 3.
Expanded 2 × 2 table relating patients who progressed by mp-MRI or Gleason grade—analysis of all patients and subgroups depending on initial GS score and previous biopsy method
| All patients (%) | |||
| Gleason score upgrade | MRI progression | No MRI progression | Total |
| Yes | 29 (53) | 0 | 29 (53) |
| No | 15 (27) | 11 (20) | 26 (47) |
| Total | 44 (80) | 11 (20) | 55 (100) |
| Patients with initial GS of 3 + 3 = 6 (%) | |||
| Gleason score upgrade | MRI progression | No MRI progression | Total |
| Yes | 24 (57) | 0 | 24 (57) |
| No | 9 (21) | 9 (21) | 18 (43) |
| Total | 33 (79) | 9 (21) | 42 (100) |
| Patients with initial GS of 3 + 4 = 7a (%) | |||
| Gleason score upgrade | MRI progression | No MRI progression | Total |
| Yes | 5 (38) | 0 | 5 (38) |
| No | 6 (46) | 2 (15) | 8 (62) |
| Total | 11 (85) | 2 (15) | 13 (100) |
| Patients with previous TRUS-GB* (%) | |||
| Gleason score upgrade | MRI progression | No MRI progression | Total |
| Yes | 14 (61) | 0 | 14 (61) |
| No | 4 (17) | 5 (22) | 9 (39) |
| Total | 18 (78) | 5 (22) | 23 (100) |
| Patients with previous FUS-GB + TRUS-GB** (%) | |||
| Gleason score upgrade | MRI progression | No MRI progression | Total |
| Yes | 15 (47) | 0 | 15 (47) |
| No | 11 (34) | 6 (19) | 17 (53) |
| Total | 26 (81) | 6 (19) | 32 (100) |
GS, Gleason score; FUS-GB, targeted MRI/US fusion-guided biopsy; TRUS-GB, 12-core systematic transrectal ultrasound-guided biopsy
*Patients that had initially only systematic TRUS-GB at the time when they were included in AS
**Patients that had initially combined FUS-GB + TRUS-GB at the time when they were included in AS