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. Author manuscript; available in PMC: 2021 Feb 17.
Published in final edited form as: Nat Struct Mol Biol. 2020 Aug 17;27(10):913–924. doi: 10.1038/s41594-020-0476-7

Fig. 1.

Fig. 1.

The architecture of DNA bound Polζ holoenzyme. a, Schematic of the primary structure of S. Cerevisiae Polζ subunits. Different colors denote each subunit. b, Near atomic resolution cryo-EM density map of DNA bound Polζ holoenzyme colored by local resolution. c, The three-dimensional reconstruction of Polζ holoenzyme viewed (left) perpendicular and parallel (right) to the DNA axis. A red dashed connector represents disordered Pol32c and the arrowhead marks the putative interaction location with PCNA. d, Cryo-EM structure of DNA bound Polζ colored by domain, and viewed from the same orientations as in (c).