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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Pediatr Neurol. 2020 Aug 5;112:14–21. doi: 10.1016/j.pediatrneurol.2020.08.003

Table 1:

Past medical history, neurologic exam findings and imaging findings for HIV-infected children with neuroimaging evidence of CVD.

ID Age Gender Significant
medical history
Neurological exam
findings
MRI findings MRA findings
1 13 F History of pulmonary tuberculosis and typhoid fever None/normal Mild cortical atrophy and an old ischemic lesion in the right cerebellum Normal
2 14 F History of syncope Positive Babinski bilaterally Bilateral multifocal punctate periventricular and subcortical white matter hyperintensities Normal
3 13 M Exposed to alcohol in utero; recurrent fevers Hypoactive reflexes consistent with HIV-associated peripheral neuropathy Punctate subcortical white matter foci of hyperintensity in the left greater than right frontal lobes Normal
4 12 F Born premature at 30 weeks None/normal Multifocal punctate white matter foci of hyperintensity in the frontal lobes bilaterally Normal
5 12 M History of learning disability Mild difficulties with rapid alternating movements on the left side; mild satelliting of the left hand on forearm rolling test. Small foci of encephalomalacia scattered in the right corona radiata, right putamen, and right frontal lobe, old right MCA territory infarct Narrowing of the right M1 segment of the MCA and small collaterals from the external carotid artery to the more peripheral MCA territory
6 14 F History of pulmonary tuberculosis Positive Babinski on the left Old infarct in the right basal ganglia and right corona radiata Normal
7 9 F History of severe malnutrition; episode of right hemiparesis two years prior that largely resolved within a month. 4+/5 right finger strength and mild slowing of rapid alternating movements with right hand. Old infarct in the territory of the left MCA Stenosis of the left internal carotid artery with small collaterals in this region