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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Pediatr Neurol. 2020 Aug 5;112:14–21. doi: 10.1016/j.pediatrneurol.2020.08.003

Table 2:

Differences in demographics, past medical history, and HIV course for HIV-infected children with and without neuroimaging evidence of CVD.

CVD+ (n = 7) CVD− (n = 24) p value
Demographics
 Age 13.2 (1.6) 13.3 (2.4) 0.85
 Sex male 2 (29%) 13 (54%) 0.39
 Socioeconomic status index 6.8 (4.8) 7.5 (2.5) 0.77
Health indicators
 Poor health by self-report 1 (14%) 2 (9%) 1.00
 History of malnutrition 1 (14%) 5 (21%) 1.00
 History of severe malnutrition 1 (14%) 2 (8%) 0.55
 Height % 10 (6-27.5) 4 (2-15) 0.24
 Weight % 24 (10-42.5) 4 (2-12.5) 0.01**
 Number of hospitalizations 1 (1-2) 1 (1-2) 0.92
 History of malaria 3 (43%) 16 (67%) 0.38
  Cerebral malaria 0 (0%) 2 (8%) 1.00
 History of TB 2 (29%) 9 (38%) 1.00
 Opportunistic infections 1 (0.5-1) 0.5 (0-1.3) 0.70
HIV specific factors
 Age of ART initiation 5 (4-6) 4 (2-7) 0.61
 Initiation of ART before 1 yr 0 (0%) 3 (13%) 1.00
 ART treatment interrupted 1 (14%) 2 (9%) 1.00
 ART adherence issues 0 (0%) 3 (13%) 1.00
 Worst WHO stage 4 2 (29%) 11 (46%) 0.67
 Most recent CD4 < 200 0 (0%) 1 (4%) 1.00
 Lowest CD4 372.1 (205.3) 455.3 (210.2) 0.37
 Viral load ever detected 3 (43%) 11 (48%) 1.00
 Protease inhibitor any use 2 (29%) 13 (54%) 0.39
 Efavirenz any use 6 (86%) 14 (58%) 0.37