Table 1:

Clinico-pathologic and molecular features.

	NOTCH rearranged benign GT	NOTCH rearranged malignant GT	Glomus tumors with no rearrangements
Number of cases	34	16	43
Sex (M:F)	29:5	8:8	19:24
Age range (median age)	22 – 87 years (52 years)	14 – 80 years (48 yrs)	14 – 84 yrs (47.5 yrs)
Location	Lower extremity – 17 Upper extremity – 9 Visceral – 5 Other - 3	Visceral – 10 (GI tract - 6, lung - 4) Lower extremity – 4 Chest wall - 2	Fingers – 22 (nailbed – 8) Lower extremity – 10 Upper extremity – 3 Visceral – 6 Bone - 3
Size	0.4 to 3.5 cm (median – 1.0 cm)	0.8 to 10.7 cm (median – 4.2 cm)	0.2 to 3.8 cm (median – 0.5 cm)
Gene rearrangements	88% - NOTCH2  9% - NOTCH3  3% - NOTCH1  76% - MIR143	88% - NOTCH2 12% -NOTCH1 69% - MIR143	No rearrangements