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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Parkinsonism Relat Disord. 2020 May 11;76:21–28. doi: 10.1016/j.parkreldis.2020.05.014

Figure 5.

Figure 5.

The PCs in the ON condition were tested for association with diagnosis, MDS-UPDRS, SAI measures and cognitive performance while adjusting for age and gender. PC 3 scores were significantly different between controls and PD participants (p = 0.02). Higher UPDRs scores were associated with higher PC 2 scores. This correlation decreased with age ( p =0.02 ). On the other hand, PC 6 correlations to UPDRS scores increased with age (p = 0.008 ). High PC 4 scores were correlated with high latency time for SAI, especially in controls (p = 0.001 ), and this correlation decreased, even reversed with age (p = 0.0001). High PC 5 scores were correlated with shorter latency on SAI irrespective of diagnosis (p = 0.03). While PC 3 scores showed a negative correlation with MOCA scores in PD participants (p = 0.02), PC 6 showed similar trends in controls (p = 0.04). Higher BNT scores were associated with higher PC 4 scores (p = 0.007) and lower PC 6 scores (p = 0.02). Both relationships were modulated by age. Note that the neuropsychological battery was conducted only once in the ON condition within 6 months of the imaging.