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. Author manuscript; available in PMC: 2021 Oct 6.
Published in final edited form as: Expert Opin Ther Targets. 2020 Oct 6;24(9):899–914. doi: 10.1080/14728222.2020.1790528

Figure 1. Schematic representation of the functional role of lncRNAs in NB pathogenesis and disease evolution.

Figure 1.

Bottom panel: Panel of oncogene-like lncRNAs and their signaling flow-through that affects malignancy characteristics (e. g., proliferation, de-differentiation, migration, invasion, angiogenesis EMT, CSC status) in NB cells, which dictates NB pathogenesis and disease evolution. Blue circles indicates the preclinically validated targeted therapeutic strategies for HR-NB.