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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Nature. 2020 Sep 23;586(7828):281–286. doi: 10.1038/s41586-020-2745-3

Extended Data Fig. 1|. Network analysis and qPCR validation of fetal brain RNAseq data.

Extended Data Fig. 1|

a, Gene ontology analysis of differentially expressed genes from E14.5 brains from ABX v.s. SPF dams (one-tailed Fisher exact, q= 0.012500, 0.017, 0.017, 0.03830902, 0.07449995, 0.07449995, 0.07449995, 0.1001733, n=3 dams). b, Quantitative RT-PCR for Ntng1 and LRRC4C expression in E14.5 brains from offspring of SPF, ABX or GF dams (Two-way ANOVA+Tukey’s, n=9, 15, 10 dams). c, Protein interaction network of genes downregulated in E14.5 brains from offspring of ABX vs. SPF dams (Benjamini-Hochberg, q<0.05, n=3 dams). d, Protein interaction networks of genes upregulated in E14.5 brains from offspring of ABX vs. SPF dams (Benjamini-Hochberg, q<0.05, n=3 dams). Mean±SEM. *p<0.05, n.s.=not statistically significant.