Table 3.
Symptoms adjusted for in the multivariate analysis, comparing breast cancer survivors with an age- and PCP-matched reference population without cancer.
Multivariate analyses, OR (95%CI)a |
|||||
LVEF (continuous) |
CVD (dichotomous) |
HADS (continuous) |
HADS-D (continuous) |
HADS-A (continuous) |
|
Concentration difficulties | 2.5 (1.6–3.9)∗ | 2.6 (1.7–3.9)∗ | 2.3 (1.5–3.6)∗ | 2.3 (1.5–3.6)∗ | 2.4 (1.5–3.8)∗ |
Forgetfulness | 1.7 (1.2–2.6)∗ | 1.8 (1.2–2.6)∗ | 1.6 (1.1–2.4)∗ | 1.6 (1.1–2.4)∗ | 1.6 (1.1–2.4)∗ |
Dizziness | 1.7 (1.2–2.4)∗ | 1.6 (1.1–2.3)∗ | 1.6 (1.1–2.3)∗ | 1.6 (1.1–2.3)∗ | 1.6 (1.1–2.3)∗ |
Nocturia | 1.5 (1.0–2.1)∗ | 1.5 (1.0–2.1)∗ | 1.5 (1.0–2.1)∗ | 1.5 (1.0–2.1)∗ | 1.5 (1.0–2.1)∗ |
Appetite loss | 2.5 (1.1–5.8)∗ | 2.2 (0.99–4.9) | 2.1 (0.9–4.6) | 2.1 (0.9–4.7) | 2.2 (0.98–4.9) |
Intermittent claudication | 2.0 (0.9–4.2) | 2.1 (0.99–4.4) | 2.1 (1.0–4.4)∗ | 2.2 (1.0–4.5)∗ | 2.1 (0.99–4.4) |
Chest pain | 1.5 (0.8–2.7) | 1.4 (0.8–2.5) | 1.4 (0.8–2.5) | 1.5 (0.8–2.7) | 1.4 (0.8–2.6) |
Abdominal bloating | 1.4 (0.95–2.1) | 1.4 (0.97–2.1) | 1.3 (0.9–2.0) | 1.4 (0.9–2.0) | 1.3 (0.9–2.0) |
OR = Odds Ratio, unadjusted.
∗Significant.
The multivariate analysis only performed when the odds ratio is 1.5 or higher. Data were adjusted for left ventricular ejection fraction (LVEF), cardiovascular disease (CVD), and for scores on the HADS, HADS-D (depression subscale), and HADS-A (anxiety subscale).