Table 33.

Clinical signs—cardiovascular and pulmonary.

	N (%)a
Cardiovascular
Prolonged QTc (≥ 500 ms)	364 (5.1)
Prolonged QRS (≥ 120 ms)	105 (1.5)
Myocardial injury or infarction	64 (1.4)
Ventricular dysrhythmia	55 (0.8)
AV block (> 1st degree)	22 (0.3)
Total	610 (8.5)
Pulmonary
Respiratory depression	597 (8.3)
Aspiration pneumonitis	130 (1.8)
Acute lung injury/ARDS	117 (1.6)
Asthma/reactive airway disease	46 (0.6)
Total	890 (12.4)

ARDS acute respiratory distress syndrome

^aPercentage based on the total number of cases reported to the Registry in 2019 (N = 7177); 1291 Registry cases (18.0%) reported at least one cardiac or pulmonary clinical effect. Cases may be associated with more than one sign or symptom