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Oct4 regulates endothelial lineage-restricted differentiation through the AKT/NF-κB-p65 pathway. (A) WB detected that the knockdown of Oct4A activated p-AKT, p-p65, and CD105; these changes are in line with the expression of Oct4B1. (B) siOct4B1 can reverse the expression trend of AKT/NF-κB-p65 by the knockdown of Oct4A. (C) siOct4B1 can reverse the expression trend of NF-κB-p65, CD105 by AKT activator SC-79.
