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. 2020 Sep 16;22:445–455. doi: 10.1016/j.omtn.2020.09.007

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Knockdown of hsa_circ_0001955 Suppressed Proliferation, Migration, and Invasion of HCC

(A) The knockdown effect of siRNAs targeting hsa_circ_0001955 in SMMC7721 and HCCLM3. (B) Silencing of hsa_circ_0001955 inhibited cell growth of HCC. (C) Suppression of hsa_circ_0001955 expression weakened SMMC7721 migration. (D) Suppression of hsa_circ_0001955 expression weakened HCCLM3 migration. (E) Knockdown of hsa_circ_0001955 impeded SMMC7721 invasion. (F) Knockdown of hsa_circ_0001955 impeded HCCLM3 invasion. Scare bars: 100 μm. ∗p < 0.05.