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. 2020 Sep 16;22:445–455. doi: 10.1016/j.omtn.2020.09.007

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© 2020 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

miR-145-5p Was a Binding miRNA of hsa_circ_0001955 in HCC

(A) hsa_circ_0001955, with the most possibility, located in cytoplasm predicted by lncLocator. (B) Four common miRNAs (miR-1252-5p, miR-1296-5p, miR-145-5p, and miR-516a-5p) of hsa_circ_0001955 were predicted by starBase and CRI (Circular RNA Interactome). (C) The expression of miR-1252-5p in HCC. (D) The expression of miR-1296-5p in HCC. (E) The expression of miR-145-5p in HCC. (F) The expression of miR-516a-5p in HCC. (G) The prognostic value of miR-1252-5p in HCC. (H) The prognostic value of miR-1296-5p in HCC. (I) The prognostic value of miR-145-5p in HCC. (J) The prognostic value of miR-516a-5p in HCC. (K) miR-145-5p was identified as the most potential miRNA of hsa_circ_0001955 by combination of expression and survival analyses. (L) The direct relationship between miR-145-5p and hsa_circ_0001955 was determined by dual-luciferase reporter assay. ∗p < 0.05. ns, represented no significant difference.