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ULK1 loss suppresses the expression of human cholesterogenic genes (A,B) Representative immunoblot showing KD efficiency of ULK1 and RNA-seq derived transcriptomic pathway analysis in HepG2 cells treated with ± Ulk1 siRNA (Thermo Fisher Scientific, s15965; 10 nM/72 h). (C) qRT-PCR validation of mevalonate/cholesterol biosynthesis pathway genes ± Ulk1 siRNA (10 nM/72 h) in HepG2 cells. Values are means ± SD (n = 4), ∗p < 0.05.
