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. 2020 Sep 30;11:590787. doi: 10.3389/fphys.2020.590787

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Copyright © 2020 Tamanna, Clifton, Rae, van Helden, Lumbers and Pringle.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the RAS cascade. ACE, angiotensin converting enzyme; ACE2, angiotensin converting enzyme 2; NEP, neprilysin; AT₁R, Angiotensin II type 1 receptor, AT₂R; Angiotensin II type 2 receptor.