Table 5.
Brain-associated lesions | CeMV (n = 16) | HV (n = 13) | Brucella sp. (n = 7) | T. gondii (n = 6) | Nasitrema sp. (n = 1) | |||||
---|---|---|---|---|---|---|---|---|---|---|
Animals (n) | Percentage (%) | Animals (n) | Percentage (%) | Animals (n) | Percentage (%) | Animals (n) | Percentage (%) | Animals (n) | Percentage (%) | |
Meningitis | 16 | 100 | 10 | 76.9 | 7 | 100 | 5 | 83.3 | 1 | 100 |
Minimal | 7 | 43.7 | 4 | 30.8 | 0 | 0 | 5 | 83.3 | 1 | 100 |
Mild | 7 | 43.7 | 5 | 38.5 | 0 | 0 | 0 | 0 | 0 | 0 |
Moderate | 1 | 6.25 | 0 | 0 | 2 | 28.6 | 0 | 0 | 0 | 0 |
Severe | 1 | 6,25 | 1 | 7.7 | 5 | 71.4 | 0 | 0 | 0 | 0 |
Perivascular cuffings | 16 | 100 | 11 | 84.6 | 6 | 85.7 | 6 | 100 | 1 | 100 |
Minimal | 4 | 25 | 4 | 30.8 | 0 | 0 | 6 | 100 | 1 | 100 |
Mild | 6 | 37.5 | 4 | 30.8 | 0 | 0 | 0 | 0 | 0 | 0 |
Moderate | 6 | 37.5 | 1 | 7.7 | 4 | 57.1 | 0 | 0 | 0 | 0 |
Severe | 0 | 0 | 2 | 15.4 | 2 | 28.6 | 0 | 0 | 0 | 0 |
Microgliosis | 11 | 68.7 | 10 | 76.9 | 4 | 57.1 | 4 | 66.7 | 0 | 0 |
Minimal | 9 | 56.22 | 6 | 46.1 | 3 | 42.9 | 4 | 66.7 | 0 | 0 |
Mild | 2 | 12.5 | 4 | 30.8 | 1 | 14.3 | 0 | 0 | 0 | 0 |
Moderate | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
INCIBs | 2 | 12.5 | 6 | 46.1 | 0 | 0 | 0 | 0 | 0 | 0 |
Malacia | 4 | 25 | 5 | 38.5 | 2 | 28.6 | 3 | 50 | 1 | 100 |
Minimal | 3 | 18.7 | 2 | 12.5 | 2 | 28.6 | 2 | 33.3 | 0 | 0 |
Mild | 1 | 6.2 | 3 | 23.1 | 0 | 0 | 1 | 16.7 | 0 | 0 |
Moderate | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 100 |
Severe | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuronal necrosis and neuronophagia | 10 | 62.5 | 9 | 69.2 | 3 | 42.9 | 4 | 66.7 | 0 | 0 |
Minimal | 7 | 43.7 | 7 | 53.8 | 0 | 0 | 3 | 50 | 0 | 0 |
Mild | 2 | 12.5 | 2 | 15.4 | 1 | 14.3 | 1 | 16.7 | 0 | 0 |
Moderate | 1 | 6.25 | 0 | 0 | 2 | 28.6 | 0 | 0 | 0 | 0 |
Severe | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemorrhages | 9 | 56.2 | 6 | 46.1 | 0 | 0 | 1 | 16.7 | 0 | 0 |
Oedema | 4 | 25 | 2 | 15.4 | 0 | 0 | 2 | 33.3 | 0 | 0 |
Associated brain lesions | 11 | 68.75 | 1 | 7.7 | 4 | 57.1 | 6 | 100 | 0 | 0 |
Pyogranulomatous inflammation | 3 | 18.7 | 0 | 0 | 3 | 42.8 | 6 | 100 | 0 | 0 |
Syncytia | 4 | 25 | 1 | 7.7 | 0 | 0 | 0 | 0 | 0 | 0 |
Vasculitis | 3 | 18.7 | 0 | 0 | 2 | 28.6 | 0 | 0 | 0 | 0 |
Fibrinoid necrosis of vessels | 0 | 0 | 0 | 0 | 2 | 28.6 | 0 | 0 | 0 | 0 |
Tissue cysts | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 66.7 | 0 | 0 |
Lesions in other regions | 13 | 81.25 | 7 | 53.8 | 7 | 100 | 2 | 33.3 | 0 | 0 |
Ventriculitis | 1 | 6.2 | 0 | 0 | 1 | 14.3 | 0 | 0 | 0 | 0 |
Cerebellitis | 3 | 16 | 0 | 0 | 3 | 42.9 | 2 | 33.3 | 0 | 0 |
Myelitis | 4 | 25 | 2 | 15.4 | 4 | 57.1 | 0 | 0 | 1 | 100 |
choroiditis | 4 | 25 | 5 | 38.5 | 3 | 42.9 | 1 | 16.7 | 0 | 0 |
Polyradiculoneuritis | 1 | 6.2 | 0 | 0 | 5 | 71.4 | 0 | 0 | 0 | 0 |
CeMV, Cetacean Morbillivirus; HV, Herpesvirus; T. gondii, Toxoplasma gondii. Bold numbers indicate n and percentages of main CNS lesions observed in each group of etiological agents.