Figure 4.

An N-linked glycan attached to Asn35 of human Toll-like receptor 4 (A: PDB entry 2z62 [68]). Model iteratively rebuilt by PDB-Redo as shown in steps B and C [41]. Pictures at the top depict glycoprotein models of the region of interest and electron-density maps of the glycan chain (grey: 2mFo DFc map, green and red: mFo DFc difference density map). Pictures at the bottom depict the SNFG representations of glycan chains, their WURCS sequence and accession IDs to relevant databases (taken directly from Privateer's CCP4i2 report).