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. 2020 Sep 22;21(18):6960. doi: 10.3390/ijms21186960

Table 1.

Histopathological characteristics of lungs infected by SARS-CoV-2.

Characteristics SARS-CoV-2 Infection
Gross Pathology
  • (a)

    multiple areas of congestion

  • (b)

    edematous lungs

  • (c)

    >gross weights

  • (d)

    pulmonary embolism

Microscopic examination
  • (a)

    diffuse alveolar damage

  • (b)

    severe capillary congestion

  • (c)

    interstitial mononuclear cell infiltrates

  • (d)

    multinucleated syncytial cells with atypical enlarged pneumocytes

  • (e)

    microthrombosisa

Pathogenesis Combination of direct virus-induced cytopathic effects, immunologic injury, and microvascular damage induced by cytokines