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. 2020 Sep 14;9(9):862. doi: 10.3390/antiox9090862

Figure 2.

Figure 2

Lactate dehydrogenase and malate dehydrogenase enzyme activity in WT and NHERF1 KO mouse kidneys. Two to 4-month-old male C57BL/6J WT and NHERF1 KO mice were given cisplatin (20 mg/kg dose IP) or vehicle (saline) and sacrificed after 72 h as described in the Methods section. (A) Lactate dehydrogenase (LDH) enzyme activity was determined from kidney cortex tissue of these mice. Data are mean ± SEM (WT vehicle n = 3), (KO vehicle n = 4), (WT cisplatin n = 3), and (NHERF1 KO cisplatin n = 5). No significant differences were recorded. (B) Malate dehydrogenase (MDH) enzyme activity was determined from the kidney cortex tissue of these mice. Data are mean ± SEM (WT vehicle n = 3), (KO vehicle n = 4), (WT cisplatin n = 3), (NHERF1 KO cisplatin n = 5). No significant differences were reported.