Table 1.
Identified proteins with expression significantly altered in the hippocampus of rats of exposed group (Pb) vs. Control.
| Accession Id a | Protein Description | Score | Fold Change |
|---|---|---|---|
| Pb | |||
| P0DMW1 | Heat shock 70 kDa protein 1B | 4870 | −0.932 |
| P09951 | Synapsin-1 | 18,756 | −0.914 |
| P0DMW0 | Heat shock 70 kDa protein 1A | 4870 | −0.896 |
| P10719 | ATP synthase subunit beta, mitochondrial | 232,442 | −0.835 |
| P04631 | Protein S100-B | 205,290 | −0.835 |
| Q63537 | Synapsin-2 | 41,092 | −0.819 |
| P47861 | Synaptotagmin-5 | 2245 | −0.795 |
| P29101 | Synaptotagmin-2 | 2245 | −0.763 |
| P21707 | Synaptotagmin-1 | 20,604 | −0.748 |
| P10888 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | 14,314 | −0.625 |
| P00406 | Cytochrome c oxidase subunit 2 | 42,862 | −0.538 |
| P47819 | Glial fibrillary acidic protein | 14,060 | 1.062 |
| P61765 | Syntaxin-binding protein 1 | 59,845 | 1.073 |
| P30904 | Macrophage migration inhibitory factor | 38,694 | 1.094 |
| P11275 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 181,954 | 1.105 |
| P15791 | Calcium/calmodulin-dependent protein kinase type II subunit delta | 62,682 | 1.105 |
| P08413 | Calcium/calmodulin-dependent protein kinase type II subunit beta | 80,840 | 1.127 |
| P11730 | Calcium/calmodulin-dependent protein kinase type II subunit gamma | 66,045 | 1.127 |
| P34058 | Heat shock protein HSP 90-beta | 16,345 | 1.197 |
| P10818 | Cytochrome c oxidase subunit 6A1, mitochondrial | 30,209 | 1.284 |
| P07825 | Synaptophysin | 42,961 | 1.310 |
| P32551 | Cytochrome b-c1 complex subunit 2, mitochondrial | 4014 | 1.323 |
| P02650 | Apolipoprotein E | 4894 | − |
| P21571 | ATP synthase-coupling factor 6, mitochondrial | 31,889 | + |
| Q7TNJ2 | ATP-binding cassette sub-family A member 7 | 3891 | + |
| P27139 | Carbonic anhydrase 2 | 12,017 | − |
| P12075 | Cytochrome c oxidase subunit 5B, mitochondrial | 23,587 | − |
| P24942 | Excitatory amino acid transporter 1 | 27,055 | − |
| P04906 | Glutathione S-transferase P | 9312 | + |
| + 219 proteins with different status of regulation | |||
a Accession ID according to the Uniport.org database. Positive and negative values of fold change indicate up- and downregulated proteins, respectively. Signs of + or − indicates exclusive expression in the Pb group and the control group, respectively. Results of the comparison between the Pb group and the control group.