Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 11;9(9):853. doi: 10.3390/antiox9090853

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Restraint stress (A) increases circulating corticosterone (CORT), (B) reduces expression of glucocorticoid receptor (Nr3c1) and modulates mRNA expression of hepatic mediators of glucocorticoid bioavailability including (C) corticosteroid-binding globulin (CBG; Serpina6), (D) hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), and (E) hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) compared to unstressed (US) rats (n = 6–8/group). Results in (C,E) were analyzed using one-way ANOVA with Fisher’s LSD test; (A,B,D) were analyzed using non-parametric Kruskal-Wallis test with Dunn’s post-test. Data are expressed as mean ± SEM, * p < 0.05 and ** p < 0.01.