Figure 3.

Effectiveness of (E)-piplartine in the treatment of chronic cutaneous leishmaniasis. Lesion size was measured four times (day 0, day 35, day 50, and day 100) and expressed as a mean of the group in mm. At end of the experiment, lesion size of (E)-piplartine vs. glucantime treated mice groups did not show statistically significant differences with p-value > 0.800; untreated control group vs. (E)-piplartine and glucantime showed significant differences with p-value < 0.000 *.