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League table showing effect estimates of the assessed complement C5 inhibitors (eculizumab vs. ravulizumab) against the comparators on three outcomes (acute kidney injury (green), thrombotic microangiopathy (blue), and hemolysis (red)) (clinical trials). aHUS, atypical hemolytic uremic syndrome; AKI, acute kidney injury; PNH, paroxysmal nocturnal hemoglobinuria; TMA, thrombotic microangiopathy.
