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. 2020 Sep 16;8(9):355. doi: 10.3390/biomedicines8090355

Figure 4.

Figure 4

Figure 4

Forest and funnel plots showing effect estimates of eculizumab (real-life NRSI) in (a) hemolysis in PNH, (b) TMA in aHUS, and (c) AKI in aHUS. aHUS, atypical hemolytic uremic syndrome; AKI, acute kidney injury; CI, confidence interval; M–H, Mantel–Haenszel test; NRSI, non-randomized studies of the effects of interventions; PNH, paroxysmal nocturnal hemoglobinuria; SE, standard error; TMA, thrombotic microangiopathy.