Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Forest and funnel plots showing effect estimates of eculizumab for (a) clinical trials and (b) real-life NRSI in thrombotic events in PNH, and for (c) clinical trials and (d) real-life NRSI in CKD apparition/progression in PNH. CI, confidence interval; CKD, chronic kidney disease; M–H, Mantel–Haenszel test; NRSI, non-randomized studies of the effects of interventions; PNH, paroxysmal nocturnal hemoglobinuria; SE, standard error.
