Skip to main content
. 2020 Sep 17;21(18):6838. doi: 10.3390/ijms21186838

Figure 1.

Figure 1

Frequencies and intensities of antigen-specific T-cell responses in SCCA patients. PBMC from 17 healthy donors and SCCA patients before (n = 82) and after (n = 69) DCF chemotherapy were analyzed for antigen-specific T-cell responses by IFNᵧ ELISpot assay. A-C Intensity of positive HPV16-E6 (A), HPV16-E7 (B) and hTERT (C) specific T-cell responses in healthy donors and SCCA patients before and after DCF treatment. (D) Intensity of positive antiviral T-cell responses. Healthy donors population is represented by light gray points and SCCA patients by black points. Mann Whitney U test, where ** p < 0.01, *** p < 0.001. Median with interquartile range was indicated on graphs. Only the positive intensities of specific immune responses were indicated. (E,F) Correlation between HPV16-E6- and hTERT-specific immune responses before (E) and after DCF chemotherapy (F) in SCCA patients.