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. 2020 Sep 17;21(18):6838. doi: 10.3390/ijms21186838

Figure 2.

Figure 2

Presence of antigen-specific T-cell responses are associated with the clinical outcomes of SCCA patients. (A) The absolute lymphocyte count was analyzed in peripheral blood of SCCA patients before (n = 56) and after (n = 51) DCF chemotherapy. Kaplan-Meier curve in SCCA patients before and after DCF chemotherapy according to low absolute lymphocyte count. PBMC from SCCA patients before (n = 82) and after (n = 69) DCF chemotherapy were analyzed for antigen-specific T-cell responses by IFNᵧ ELISpot assay. (B,C) Kaplan-Meier OS curve in SCCA patients according to HPV (E6 and/or E7) (B) or hTERT (C) specific T-cell responses before and after DCF chemotherapy. Log-rank test, where p < 0.05. (D) Kaplan-Meier OS curve in SCCA patients according to antiviral-specific T-cell responses before and after DCF chemotherapy.