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. 2020 Sep 10;21(18):6615. doi: 10.3390/ijms21186615

Figure 1.

Figure 1

Explanted heart images showing pathological features of different phenotypes in ACM, adapted from Calkins (2013) [10], Thiene et al. (2016) [11], Corrado et al. (2020) [12]. (A) Gross specimen shows dilated thin RV, fatty replacement of entire RV free wall epicardium and thin fibrotic endocardium (white arrow). (B) Gross specimen shows little evidence of RV involvement, however subepicardial grey band of fibrotic tissue (black arrow) is seen in the posterolateral section of the LV. (C) Gross specimen shows fibro-fatty biventricular involvement (black arrows). (D) Histology image shows fat replacement extending from epicardium to endocardium. (E) Histology image with trichrome staining identifies fibrous scars within fat tissue. LV = left ventricle; RV = right ventricle.