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. 2020 Sep 10;21(18):6615. doi: 10.3390/ijms21186615

Figure 15.

Figure 15

Exemplar MRI and ECG finding found in ACM patients with TMEM43 mutations. (AD): CMR images of a male subject with TMEM43 p.S358L mutation. (A) Biventricular dilatation, wall motion abnormalities; (B) asynchronous contraction (red arrows); (C,D) LGE showing severe and almost concentric intra-myocardial lesions (red arrows); (E) a representative 12-lead ECG of a different patient with the same TMEM43 mutation, showing poor R-wave progression with 1-mV R-wave voltage in lead V3 and widened QRS complex. Reproduced with permission from Dominguez et al. (2020) [46].