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. 2020 Sep 18;21(18):6853. doi: 10.3390/ijms21186853

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Over-representation enrichment analysis (ORA) of gene ontology (GO), biological processes, for consistently hypomethylated gene promoters and/or CpG sites in (A) HNSCC tissue compared to control healthy tissue, (B) HNSCC tissue compared to potentially premalignant oral lesions, and (C) potentially premalignant oral lesions compared to control healthy tissue. The top 10 categories are shown; the fold discovery rate (FDR) adjusted significance (colored bar) is in each shown case ≤0.05.

Over-representation enrichment analysis (ORA) of gene ontology (GO), biological processes, for consistently hypomethylated gene promoters and/or CpG sites in (A) HNSCC tissue compared to control healthy tissue, (B) HNSCC tissue compared to potentially premalignant oral lesions, and (C) potentially premalignant oral lesions compared to control healthy tissue. The top 10 categories are shown; the fold discovery rate (FDR) adjusted significance (colored bar) is in each shown case ≤0.05.