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. 2020 Sep 5;21(18):6491. doi: 10.3390/ijms21186491

Figure 6.

Figure 6

Ex vivo methamphetamine exposure reduces long-term potentiation (LTP) in dorsomedial striatal synapses. (a) xy graph of time course of fEPSPs before and after high-frequency stimulation (HFS) in all groups. The arrow in (a) at 10 min points to the time of HFS. (b) Average fEPSP slope of each experimental group post HFS (10 to 50 min). Data are represented as mean ± SEM. n = 8 control slices, n = 8 methamphetamine slices, n = 5 SCH23390 + methamphetamine slices. $ p < 0.05 significant interaction; @ p < 0.05 main effect of time; + p < 0.05 main effect of treatment by repeated-measures two-way ANOVA; * p < 0.05 vs. controls; # p < 0.05 vs. SCH23390 + methamphetamine by Fisher’s LSD post hoc test.