| mRNA | messenger ribonucleic acid |
| DOTMA | N-[1-(2,3-dioleyloxy) propyl]-N,N,N-trimethylammonium chloride |
| TNF-α | tumor necrosis factor-α |
| IFN-α | interferon-α |
| COVID-19 | coronavirus disease 2019 |
| 5′ cap | five-prime cap |
| 5′ UTR | five-prime untranslated region |
| ORF | open reading frame |
| 3′ UTR | three-prime untranslated region |
| eIF | eukaryotic translation initiation factor |
| ARCA | anti-reverse cap analogs |
| DCs | dendritic cells |
| PABP | Poly (A) binding protein |
| APCs | antigen-presenting cells |
| PRRs | pattern recognition receptors |
| TLR | Toll-like receptor |
| dsRNA | double-stranded RNA |
| RIG-I | Retinoic-acid-inducible gene I |
| RLRs | RIG-I-like receptors |
| MDA5 | melanoma differentiation-associated 5 |
| IFN | type I interferon |
| CD | cluster of differentiation |
| ssRNA | single-stranded RNA |
| PAMP | pathogen-associated molecular pattern |
| ISGs | IFN-stimulated genes |
| IFIT | IFN-inducible protein with tetratricoid repeats |
| OAS | 2′-5′-oligoadenylate synthetase |
| CNE | cationic nanoemulsion |
| AIDS | acquired immune deficiency syndrome |
| HIV | human immunodeficiency virus |
| DOTAP | 1,2-dioleoyl-3trimethylammonium-propane |
| DOPE | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine |
| Th1 | T-help 1 cell |
| NSCLC | Non-small cell lung cancer |
| ZIKV | Zika virus |
| LNP | lipid nanoparticles |
| PEG | polyethylene glycol |
| DC-Cholesterol | 3β-[N-(N’,N’-dimethylaminoethane) carbamoyl] |
| PBAE | poly(β-amino ester) |
| PSA | polyethyleneimine-stearic acid |
| PEI | polyethylenimine |
| DEAE | diethylaminoethyl |
| hPBAEs | hyperbranched poly(beta amino esters) |
| PEG[Glu(DET)]2 | N-substituted polyethylene glycol-diblock-polyglutamide |
| PLGA | poly(lactic-co-glycolic acid) |
| CLAN | cationic lipid-assisted nanoparticles |
| BHEM-cholesterol | N-bis(2-hydroxyethyl)-N-methyl-N-(2-cholesteryloxycarbonyl aminoethyl) ammonium bromide |
| MHC | major histocompatibility complex |
| CTLs | cytotoxic T-lymphocytes |
| siRNA | short interfering RNA |
| SAM | self-amplifying mRNA |
| gp100 | glycoprotein 100 |
| HVJ | hemagglutinating virus of Japan |
| TB | tuberculosis |
| CMV | cytomegalovirus |
| gB | herpesvirus glycoprotein |
| HA | hemagglutinin |
| hMPV | human metapneumovirus |
| PIV3 | parainfluenza virus 3 |
| RABV-G | rabies virus glycoprotein |
| SARS-CoV | severe acute respiratory syndrome coronavirus |
| MERS-CoV | Middle East respiratory syndrome coronavirus |
| S protein | spike protein |
| prM | pre-membrane |
| E | envelope |
| VEEV | Venezuelan equine encephalitis virus |
| GAS | Group A Streptococci |
| BCG | Mycobacterium bovis Bacillus Calmette–Guérin |
| WT1 | Wilms’ Tumor-1 |
| hTERT | human telomerase reverse transcriptase |
| LAMP | lysosome-associated membrane protein |
| CEA | carcinoembryonic antigens |
| MUC1 | tumor marker expressed by MUC1 gene |
| Survivin | one of the apoptosis inhibitory protein family |
| pp65 | 65K phosphoprotein |
| MiHA | minor histocompatibility antigens |
| Melan-A | melanoma antigen recognized by T cells |
| TRP2 | tyrosinase-related protein 2 |
| SOCS 1 | cytokine signaling 1 |
| NY-ESO-1 | New York esophageal squamous cell carcinoma 1 |
| PAP | prostatic acid phosphatase |
| AML | acute myelocytic leukemia |
| GBM | glioblastoma |
| CAR | chimeric antigen receptor |
| CLDN6 | claudin 6 |
| PIPAC | pressurized intraperitoneal aerosol chemotherapy |
| FCS | fluorescence correlation spectroscopy |