Table 4.
Regulatory features co-localizing with KEAP1 CpGs.
| CpG | Regulatory Feature | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Exonic/Intronic Location | Strand | Start | End | CpG | Feat Start | Feat End | Name | Score | UCSC Track |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10613910 | 10614318 | E2F6 | 1000 | A |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10613919 | 10614347 | E2F6_(H-50) | 1000 | A |
| Exon 1 | − | 10614022 | 10614023 | cg02428100 | 10613910 | 10614318 | E2F6 | 1000 | A |
| Exon 1 | − | 10614022 | 10614023 | cg02428100 | 10613919 | 10614347 | E2F6_(H-50) | 1000 | A |
| Intron 2 | − | 10602960 | 10602961 | cg20226327 | 10602751 | 10603103 | CTCF | 1000 | A |
| Exon 3 | + | 10602877 | 10602878 | cg10505024 | 10602751 | 10603103 | CTCF | 1000 | A |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10612580 | 10614352 | POLR2A | 1000 | B |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10612955 | 10614326 | PHF8 | 1000 | B |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10613272 | 10614430 | MAX | 1000 | B |
| Exon 1 | + | 10614272 | 10614273 | cg25801292 | 10613814 | 10614366 | E2F6 | 1000 | B |
| Exon 1 | - | 10614022 | 10614023 | cg02428100 | 10612580 | 10614352 | POLR2A | 1000 | B |
| Exon 1 | − | 10614022 | 10614023 | cg02428100 | 10612955 | 10614326 | PHF8 | 1000 | B |
| Exon 1 | − | 10614022 | 10614023 | cg02428100 | 10613272 | 10614430 | MAX | 1000 | B |
| Exon 1 | − | 10614022 | 10614023 | cg02428100 | 10613814 | 10614366 | E2F6 | 1000 | B |
| Intron 2 | − | 10602960 | 10602961 | cg20226327 | 10602731 | 10603130 | CTCF | 1000 | B |
| Exon 3 | + | 10602877 | 10602878 | cg10505024 | 10602731 | 10603130 | CTCF | 1000 | B |
| Exon 3 | − | 10602691 | 10602692 | cg07695362 | 10602731 | 10603130 | CTCF | 1000 | B |
| Exon 5 | + | 10599976 | 10599977 | cg02337283 | 10599967 | 10599986 | V$GR_Q6 | 850 | C |
For each overlapping feature, the chromosomal start/end, the transcription factor name and scores are provided. Only high-confidence features (score > 800; maximum score = 1000) are reported. UCSC track A is related to transcription factor binding sites (TFBSs) from the ENCODE Project Release 3 (wgEncodeRegTfbsClusteredV3); track B is related to TFBS from the ENCODE Project Release 2 (wgEncodeRegTfbsClusteredV2); track C is related to a collection of computationally predicted TFBS (tfbsConsSites); conservation scores are computed through the Transfac Matrix and Factor Database v7.0, considering three species (human, mouse, rat). “V$GR_Q6” refers to a binding matrix associated with the NR3C1 receptor.