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. 2020 Sep 12;21(18):6678. doi: 10.3390/ijms21186678

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Atrial structural remodeling in wild-type and ALDH2*2 KI mice with chronic ethanol intoxication with and without Alda-1 treatment. (A) Representative confocal images showing the expression of transforming growth factor beta 1 (TGF-β1) and collagen I in the atria of mice. (B) Relative intensities of TGF-β1 and collagen I production were quantified. At least 10 random fields were chosen with scanning and averaging. Data are expressed as mean ± SE. n, the number of fields observed in each quantitative measurement; WT, wild-type; KI, heterozygous and homozygous ALDH2*2 KI mice; EtOH, ethanol, ** p < 0.01, *** p < 0.001.