Table 1.
Compound | R1 | R2 | R3 | R4 | R5 | R2′ | R3′ | R4′ | R5′ | X | Yield (%) |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | H | OH | H | OH | H | OH | H | H | OH | CH2 | 41 |
2 | H | OH | H | H | OH | OH | H | OH | H | CH2 | 44 |
3 | H | H | H | OH | H | OH | H | H | OH | CH2 | 79 |
4 | H | OH | H | H | OH | OH | H | H | OH | CH2 | 79 |
5 | H | OH | H | OH | H | OH | H | OH | H | CH2 | 94 |
6 | H | H | OH | OH | H | OH | H | H | OH | CH2 | 56 |
7 | H | H | H | OH | H | H | OH | OH | H | CH2 | 75 |
8 | H | H | H | OH | H | OH | H | OH | H | CH2 | 80 |
9 | (4-OH)Ph | H | H | OH | H | OH | H | H | OH | CH2 | 72 |
10 | (2,5-OH)Bn | H | H | OH | H | OH | H | H | OH | CH2 | 81 |
11 | H | OH | H | OH | H | OH | H | H | OH | NH | 95 |
12 | H | OH | H | H | OH | H | H | OH | H | NH | 56 |
13 | H | OH | H | H | OH | H | OH | OH | H | NH | 68 |
14 | H | H | OH | OH | H | H | H | OH | H | NH | 60 |
15 | H | H | H | OH | H | H | H | OH | H | NH | 84 |
16 | H | OH | H | H | OH | OH | H | H | OH | NH | 20 |
17 | (4-OH)Ph | H | H | OH | H | H | H | OH | H | NH | 68 |
18 | (2,5-OH)Bn | H | H | OH | H | OH | H | H | OH | NH | 10 |