Table 3.

HER2-associated miRNAs in single hormone receptor-positive breast tumors; log2fold change (log2FC) calculated for the mean normalized counts of each probe in compared groups—HER2(+) vs. HER2(−); miRNAs upregulated in HER2(+) tumors are marked with ↑, miRNAs downregulated in HER2(+) tumors are marked with ↓; differences estimated with Two-Way ANOVA (p-value) with Benjamini–Hochberg correction (FDR), only statistically significant results (FDR ≤ 0.2) are presented; miRNA names are according to miRBase database (v21).

miRNA	HER2 log2FC	Direction	HER2 p-Value	HER2 FDR	ER/PgR log2FC	ER/PgR p-Value	ER/PgR FDR
hsa-miR-887-5p	2.85	↑	0.003	0.130	0.42	0.990	0.998
hsa-miR-208a-3p	2.50	↑	0.012	0.156	0.79	0.541	0.847
hsa-miR-891a-5p	2.29	↑	0.020	0.160	0.85	0.473	0.826
hsa-miR-301a-5p	2.17	↑	0.026	0.160	1.26	0.178	0.811
hsa-miR-33b-5p	2.09	↑	0.024	0.160	0.69	0.598	0.864
hsa-miR-1296-3p	1.91	↑	0.007	0.130	0.53	0.675	0.898
hsa-miR-378d	1.91	↑	0.002	0.130	0.14	0.702	0.908
hsa-miR-548v	1.82	↑	0.027	0.160	0.82	0.400	0.811
hsa-miR-1295a	1.73	↑	0.005	0.130	0.73	0.338	0.811
hsa-miR-337-3p	1.54	↑	0.014	0.156	−0.11	0.480	0.827
hsa-miR-514b-5p	0.83	↑	0.023	0.160	−0.67	0.046	0.809
hsa-miR-185-5p	−0.71	↓	0.032	0.186	0.13	0.410	0.811
hsa-miR-340-5p	−0.72	↓	0.025	0.160	−0.27	0.666	0.898
hsa-miR-424-5p	−0.74	↓	0.020	0.160	−0.69	0.048	0.809
hsa-miR-106a-5p+hsa-miR-17-5p	−0.82	↓	0.007	0.130	−0.40	0.379	0.811
hsa-miR-151a-3p	−0.84	↓	0.021	0.160	0.29	0.221	0.811
hsa-miR-374a-5p	−0.91	↓	0.013	0.156	0.10	0.435	0.811
hsa-miR-141-3p	−0.92	↓	0.034	0.193	1.10	0.018	0.809
hsa-miR-26b-5p	−0.96	↓	0.025	0.160	0.54	0.110	0.809
hsa-miR-126-3p	−0.97	↓	0.006	0.130	0.20	0.255	0.811
hsa-miR-32-5p	−1.04	↓	0.017	0.160	0.19	0.349	0.811
hsa-miR-15b-5p	−1.08	↓	0.023	0.160	−0.55	0.425	0.811
hsa-miR-30d-5p	−1.12	↓	0.006	0.130	0.53	0.078	0.809
hsa-miR-1180-3p	−1.18	↓	0.008	0.142	−0.16	0.867	0.953
hsa-miR-30b-5p	−1.25	↓	0.002	0.130	0.13	0.310	0.811
hsa-miR-195-5p	−1.33	↓	0.024	0.160	0.49	0.209	0.811
hsa-miR-429	−1.39	↓	0.023	0.160	−0.27	0.997	0.998
hsa-miR-503-5p	−1.46	↓	0.011	0.156	−1.19	0.079	0.809
hsa-miR-223-3p	−1.47	↓	0.025	0.160	−1.30	0.087	0.809
hsa-miR-450a-5p	−1.60	↓	0.006	0.130	−0.74	0.397	0.811
hsa-miR-29b-3p	−1.63	↓	0.001	0.130	0.36	0.135	0.811
hsa-miR-135b-5p	−2.17	↓	0.016	0.160	−1.46	0.184	0.811
hsa-miR-660-5p	−2.30	↓	0.010	0.147	−1.49	0.167	0.811