Table 3.

GEO datasets reporting associations between miRNAs and Parkinson’s disease.

GEO Reference	Profiling Technique	Main Observations	Sample Type	Reference
GSE72962	RNA-seq	125 miRNAs are regulated in PD A set of 29 miRNAs classifies PD	Frozen brain tissue from pre-frontal cortex of 29 PD patients and 33 controls.	[197]
GSE16658	Microarray	18 miRNAs are regulated in PD 11 miRNAs are over-represented in pathways linked to PD	PBMCs of 19 PD patients and 13 controls	[53]
GSE110719	RNA-seq	99 miRNAs are regulated in the substantia nigra of PD patients	Fibroblasts and iPSCs from 6 controls and nine PD Dopaminergic neurons from five controls and six PD.	[198]
GSE97285	RNA-seq	Several groups of miRNAs are regulated in PD at different disease progression stages	Brain samples from the amygdala—14 PD and 14 controls	[199]
GSE40915	RNA-seq	16 miRNAs are regulated in blood leukocytes of PD patient’s pre-treatment 11 miRNAs are regulated after brain stimulation, among which five vary inversely to disease evolution.	Blood leukocytes from nine PD and three controls.	[200]