Table 2.

Biomarkers identified after differentiation stimuli from mesenchymal stem/progenitor cells (MSCs) derived from nasal tissue or nasal polyps. Polyp derived mesenchymal stem cells (PO-MSCs) can differentiate, under specific stimuli, into adipocytes, osteocytes, chondrocytes, and neuron-like cells. The terminal differentiation of PO-MSCs towards cells of mesodermal or non-mesodermal origin results in the expression of lineage-specific markers.

Differentiation	Markers	Ref.
Adipogenesis	PPARγ, FABP4,	[50,62]
Osteogenesis	Runx2, Osteocalcin	[62]
Chondrogenesis	Sox9, Col2A	[62]
Neuron-like cells	NF-H, NF-L, TuJ1, Nestin, GM-CSF	[62,64,65,75]