Figure 5.

Anti-apoptotic effect of ethyl acetate extract of Ribes diacanthum Pall (RDP) on glutamate-induced apoptosis in HT-22 cells. HT-22 cells were seeded in a 60 mm dish and then incubated for 24 h. The cells were challenged with glutamate after pre-incubation with or without RDP (0–50 µg/mL) for 30 min. After twelve h, the expression of Bcl-2, Bax, AIF, calpain. cytochrome c, and β-actin was measured. The data are obtained from three independent experiments. * p < 0.05 and ** p < 0.01 versus vehicle control group. ## p < 0.01 versus glutamate-treated group–indicates absence.