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Activation of the ERK/BDNF/TrkB pathway in HT-22 cells by ethyl acetate extract of Ribes diacanthum Pall (RDP). The experiments were performed as elaborated in the Materials and Methods. The data were obtained from three independent experiments. (A) p-ERK, and (B) BDNF, p-CREB, β-actin, p-TrkB, and total TrkB. * p < 0.05, and ** p < 0.01 versus vehicle control group. ## p < 0.01 versus glutamate-treated group–indicates absence, + indicates presence.
