Aβ |
amyloid β |
AD |
Alzheimer’s disease |
ALS |
autophagic-lysosomal system |
BBB |
Blood-brain barrier |
CAZy |
Carbohydrate Active Enzymes |
Cer |
ceramide |
CNS |
central nervous system |
EGFR |
epidermal growth factor receptor |
ER |
endoplasmic reticulum |
ERT |
enzyme replacement therapy |
Fuc |
fucose |
Gal |
galactose |
GalNAc |
N-acetylgalactosamine |
GD |
Gaucher disease |
GDNF |
glial derived neurotropic factor |
GH |
glycosyl hydrolase |
Glc |
glucose |
GlcCer |
glucosylβ-ceramide |
GlcNAc |
N-acetylglucosamine |
GLTP |
Glycolipid transfer protein |
GPI |
glycosylphosphatidylinositol |
GSL |
glycosphingolipid |
GT |
glycosyltransferase |
HPLC |
high pressure liquid chromatography |
HPAEC |
high performance anion exchange chromatography |
LacCer |
lactosyl-ceramide |
LC |
liquid chromatography |
LMP |
lysosomal membrane permeability |
LRP |
laminin receptor protein |
LSD |
lysosomal storage disease |
Lyso-GSL |
GSL lacking the fatty acid moiety |
Man-6-P |
mannose-6-phosphate |
MS |
mass spectrometry |
Neu5Ac |
5-N-acetylneuraminic acid |
Neu5Gc |
5-N-glycolylneuraminic acid |
NMR |
nuclear magnetic resonance |
PD |
Parkinson’s disease |
PPCA |
Cathepsin A |
SAP |
saposin |
SD |
Sandhoff disease |
SNCA |
α-synuclein |
TNF |
tumor necrosis factor |
TSD |
Tay–Sachs disease |
UPS |
ubiquitin-proteasome system |