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. 2020 Sep 19;21(18):6881. doi: 10.3390/ijms21186881
amyloid β
AD Alzheimer’s disease
ALS autophagic-lysosomal system
BBB Blood-brain barrier
CAZy Carbohydrate Active Enzymes
Cer ceramide
CNS central nervous system
EGFR epidermal growth factor receptor
ER endoplasmic reticulum
ERT enzyme replacement therapy
Fuc fucose
Gal galactose
GalNAc N-acetylgalactosamine
GD Gaucher disease
GDNF glial derived neurotropic factor
GH glycosyl hydrolase
Glc glucose
GlcCer glucosylβ-ceramide
GlcNAc N-acetylglucosamine
GLTP Glycolipid transfer protein
GPI glycosylphosphatidylinositol
GSL glycosphingolipid
GT glycosyltransferase
HPLC high pressure liquid chromatography
HPAEC high performance anion exchange chromatography
LacCer lactosyl-ceramide
LC liquid chromatography
LMP lysosomal membrane permeability
LRP laminin receptor protein
LSD lysosomal storage disease
Lyso-GSL GSL lacking the fatty acid moiety
Man-6-P mannose-6-phosphate
MS mass spectrometry
Neu5Ac 5-N-acetylneuraminic acid
Neu5Gc 5-N-glycolylneuraminic acid
NMR nuclear magnetic resonance
PD Parkinson’s disease
PPCA Cathepsin A
SAP saposin
SD Sandhoff disease
SNCA α-synuclein
TNF tumor necrosis factor
TSD Tay–Sachs disease
UPS ubiquitin-proteasome system