Table 2.

Disorders of glycosphingolipid biosynthesis.

Name of Disease	Gene	Enzyme	Affected GSL	MIM Phenotype No.
Spastic Paraplegia (Type 26)	B4GALNT1	β1,4GalNAc-transferase	GM2, GM1, etc.	609195
West Syndrome	ST3GAL III	α2,3Sialyltransferase 3	GM1, GD1a, etc.	615006, 611090
Amish Infantile Epilepsy	ST3GAL V	α2,3Sialyltransferase 9 (GM3 synthase)	LacCer	609056