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. 2020 Sep 12;21(18):6687. doi: 10.3390/ijms21186687

Figure 7.

Figure 7

PCS induced oxidative stress. Unilateral nephrectomized mice were intraperitoneally injected with PCS (0, Control; and 100 mg/kg, PCS) and the PCS-injected mice were orally given with AST-120 (400 mg/kg, PCS/AST-120) for 7 weeks. The prefrontal cortical tissues (A), urine (B, 24 h), and blood (C) were collected and subjected to the measurement of MDA levels. The prefrontal cortical tissues were collected and subjected to the measurement of GSH content (D). The prefrontal cortical tissues were collected and subjected to the measurement of 8-OH-dG content (E). Proteins were extracted from the isolated prefrontal cortical tissues and subjected to a Western blot test with the indicated antibodies. Representative blots (F) and the quantitative data (G) are shown. * p < 0.05 vs. control group and # p < 0.05 vs. PCS group, n = 8.