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. 2020 Sep 10;21(18):6631. doi: 10.3390/ijms21186631

Table 1.

IC50 values of BrdU and EdU for DNA repair-deficient cells.

Cell Line BrdU
(μM)
EdU
(μM)
Ratio
BrdU/EdU
Affected Pathways
CHO 15 0.088 170 n.a.
V3 0.54 0.025 21 NHEJ
xrs5 0.63 0.023 27 NHEJ
XR-1 0.56 0.022 25 NHEJ
irs1SF 0.30 0.0027 111 HR
51D1 0.54 0.0021 257 HR
KO40 0.44 0.011 40 Fanconi Anemia
PADR9 0.38 0.010 38 poly(ADP-ribosylation)