Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 21;21(18):6938. doi: 10.3390/ijms21186938

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Comparative pathway analysis between the two datasets. (A) Venn diagrams showing the number of significantly dysregulated genes in each disease (FUS- and SOD1-ALS) and the observed overlap across comparisons. (B) KEGG pathways that are significantly enriched in DEGs specific for each FUS-ALS (upper part) and SOD1-ALS (lower part) disease. (C) The significant KEGG pathways (upper part) and Gene Ontology (GO) analysis of biological processes (lower part) enriched by the DEGs shared between FUS-ALS and SOD1-ALS (present study vs. GSE106382) respectively. X-axis represents the statistical significance of the enrichment (-log10(p-value)). Color coding represents disease subtypes.