Table 2.

Patient/proband characteristics.

Genotype	Cell Culture Model	Sex	Age at Biopsy (Years)	Mutation	Family History	Age of Disease Onset	Clinical Phenotype	Disease Duration (Months)
Controls	hiPSC
		female	48	-	-	-	-	-
		male	60	-	-	-	-	-
		female	45	-	-	-	-	-
		female	50	-	-	-	-	-
FUS-ALS	hiPSC
		female	58	p.R521C *	Pos. for ALS	57	spinal	7
		female	65	p.R521L *	Pos. for ALS	61	spinal	60
SOD1-ALS	hiPSC
		Male	59	p.R115G	Pos. for ALS	n.a	spinal	n.a
		female	46	p.D90A *	Pos. for ALS	n.a	Spinal	n.a

n.a: not available; * two clones were used in the current study.