Figure 3.

Activity of 1,4-disubstituted-1,2,3-triazole compounds against Leishmania amazonensis intracellular amastigotes. Parameters of infection of BALB/c peritoneal macrophages infected with L. amazonensis and treated with triazole compounds (A–L) or mltefosine (M–O) for 24 h. The data represent mean ± standard deviation of two independent experiments performed in quadruplicate. * p < 0.05 and ** p < 0.01 when compared with the control group by Kruskal–Wallis followed by Dunn’s multiple comparisons test.