WHO	World Health Organization
IC50	inhibitory concentration of 50%
CC50	cytotoxicity concentration of 50%
SI	selectivity index
TPSA	topological polar surface area
PAINS	pan-assay interference compounds
VDss	steady state volume of distribution
CNS	central nervous system
BBB	blood-brain barrier
hERG	human ether-a-go-go gene
AMES	Salmonella/microsome mutagenicity assay
LOAEL	lowest dose of a compound that results in an observed adverse effect
OCT2	organic cation transporter 2,
DMSO	dimethyl sulfoxide
MTT	3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide